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ObjectiveTo understand the cooperative work and mechanism in the corona virus disease 2019 containment action by the support-to-Hebei epidemiological investigation group formed by five provinces， summarize the existing challenges， and discuss the relevant mechanism， so as to provide evidence for future support actions. MethodsA questionnaire survey was used to investigate the members from five provinces of the support-to-Hebei epidemiological investigation team. The content included basic information， work situation， problems in cooperative work， and suggestions in support mechanisms. ResultsA total of 104 questionnaires were issued， of which 101 valid questionnaires were collected with an effective response rate of 97.12%. The proportions of respondents who participated in the epidemic-related data preparation， case investigation， technical training， supervision of key venues， and specimen collection was 93.07%， 85.15%， 81.19%， 65.35%， and 44.55%， respectively. The respondents believed that information sharing channel of local epidemic situation was blocked （95.05%）， coordination mechanism among local departments was insufficient （84.16%）， communication and coordination mechanism among the dispatch institutions， support team， and local departments was unperfect （84.16%）， management of the dispatch institutions to the support team was relatively loose （79.21%）， dispatch institutions failed to make full use of professional advantages of the support team （72.28%）， and majority of the support team members engaged in a single profession （59.41%）. The respondents suggested that local departments should improve the information sharing mechanism （95.05%）， strengthen communication and coordination among the dispatch institutions， support team， and local departments （92.08%）， and dispatch institutions should clarify the tasks and responsibilities of the support team （91.09%）， formulate cross-regional emergency support plans （87.13%） and evaluation plans of support action （72.28%）. ConclusionIn order to ensure the efficiency and accuracy of future support actions， it is necessary to improve the mechanism of emergency coordination， communication and matching， response procedures， team management， and support evaluation.
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A questionnaire was used to investigate the emergency training needs of novel coronavirus pneumonia of disease prevention and control institutions in provinces, deputy provincial level regions and cities specifically designated in the state plan, and the effect evaluation of emergency training activities conducted by Chinese Center for Disease Control and Prevention (China CDC). The results showed that 67.4% of 47 disease prevention and control institutions (31/46) believed that the emergency training at the initial stage of the epidemic should be conducted as soon as possible, and the form of network training should be given priority. The training should focus on the urgently needed technologies such as epidemiological investigation, formulation and response of prevention and control strategies, laboratory testing, etc. The teaching materials should highlight pertinence and practicability and be presented in the form of electronic video. The average satisfaction score of the video training conducted by China CDC was (8.81±1.125) and the score of audio-video courseware was (8.97±0.893). The needs analysis and evaluation of novel coronavirus pneumonia prevention and control in disease prevention and control institutions could provide reference for the follow-up training and improve the emergency training management.
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Humans , COVID-19 , China/epidemiology , Pneumonia/prevention & control , SARS-CoV-2 , Surveys and QuestionnairesABSTRACT
Public health physician is one of the four statutory types of physicians in China, but there is no consensus on their connotation. The main problems are that public health physician is confused with those who perform public health tasks, the relationship between public health physician and clinician and the connotation of prescription right is not clear, and there is limitation in public health education and relevant laws and regulations. Public health physician is positioned as professionals who monitor, investigate, evaluate, and intervene in population health-related issues. It is suggested to retain the practicing qualification of public health physicians and highlight the attribute of public health physicians′ prescribing the prescriptions for community health. Encourage public health physicians to obtain qualification for clinicians to individual prescription, Encourage clinicians to access to public health physician qualification. Improve public health school education, take the pilot of public health physician standardization training, cultivate "prevention and treatment combined" physician.
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Objective@#To understand the internship of students majoring in preventive medicine in 6 colleges and universities in China, and provide reference suggestions for the improvement of internship arrangement.@*Methods@#By using the method of combined clustering and convenient sampling, the fifth grades students majoring in preventive medicine in six universities in the eastern, central and western China were surveyed by using questionnaires to collect the information of their attitudes (to) and suggestions for clinical and public health internships.@*Results@#A total of 596 students were surveyed. In terms of the benefits of clinical internship and public health internship, students who thought that the internship was fruitful accounted for >88%, and more students thought that reform is needed in clinical internship compared with public health internship. In clinical internship, the students through that the time arrangement was not appropriate enough (95, 39.58%), the content should be more detailed and in-depth (73, 30.42%) and the content did not conform to the professional direction (54, 22.50%). In public health internship, the students thought that the time arrangement was not appropriate (77, 45.56%), the content should be more detailed and standardized (65, 38.46%) and the types of internship bases should be more diversified (20, 11.83%).@*Conclusions@#The undergraduates majoring in preventive medicine felt to be benefited from clinical practice and public health internships and thought they are of necessity. At the same time, there are still many problems which needs to be improved in the two types of internships. It is necessary to make joint efforts from students, teachers, colleges and practice bases to promote the continuous improvement of undergraduate internship.
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The process of globalization increases the risk of global transmission of infectious diseases,resulting in pressure for country's prevention and control of imported infectious disease.Based on the risk assessment of disease importation and local transmission,a strategy that conducting importation prevention and routine prevention and control before the importation of disease and taking emergency control measures after the importation of disease was developed.In addition,it is important to take part in global infectious disease response action,aid the countries with outbreak or epidemic to actively decrease the risk of disease importation.
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The process of globalization increases the risk of global transmission of infectious diseases,resulting in pressure for country's prevention and control of imported infectious disease.Based on the risk assessment of disease importation and local transmission,a strategy that conducting importation prevention and routine prevention and control before the importation of disease and taking emergency control measures after the importation of disease was developed.In addition,it is important to take part in global infectious disease response action,aid the countries with outbreak or epidemic to actively decrease the risk of disease importation.
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Objective:To establish the HPLC specific chromatogram and provide comprehensive evaluation of Xanthii fructus from different regions.Methods:The HPLC analysis was performed on an Alltima C18 column (250 mm ×4.6 mm,5μm) with acetonitrile-0.1％phosphoric acid solution as the mobile phase with gradient elution at a flow rate of 0.8 ml· min-1 .The detection wavelength was 278 nm.The column temperature was 25℃.The software"Similarity Evaluation System for Chromatographic Fingerprint of TCMs"was employed to carry out the similarity analysis of the samples from Henan , Jilin, Anhui and the other regions .Results:The specific chromatogram was preliminarily constructed and 5 common peaks with chlorogenic acid as the reference were identified .Conclusion:The method is scientific basis of the quality assessment of Xanthii fructus with convenient and reliable properties .
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Objective In order to understand the current management status on education/ training and needs for training among new employees working at the provincial CDC in China during 2012-2014,so as to provide basis for setting up related programs at the CDC levels.Methods Based on data gathered through questionnaire surveys run by CDCs from 32 provincial and 5 specifically-designated cities,microsoft excel was used to analyze the current status on management of education and training,for new employees.Results There were 156 management staff members working on education and training programs in 36 CDCs,with 70％ of them having received intermediate or higher levels of education.Large differences were seen on equipment of training hardware in different regions.There were 1 214 teaching staff with 66 percent in the fields or related professional areas on public health,in 2014.5084 new employees conducted pre/post training programs,from 2012 to 2014 with funding as 750 thousand RMB Yuan.99.5％ of the new employees expressed the needs for further training while.74％ of the new staff members expecting a 2-5 day training program to be implemented.79％ of the new staff members claimed that practice as the most appropriate method for training.Conclusions Institutional programs set for education and training at the CDCs need to be clarified,with management team organized.It is important to provide more financial support on both hardware,software and human resources related to training programs which are set for new stuff members at all levels of CDCs.
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Objective In order to understand the current management status on education/ training and needs for training among new employees working at the provincial CDC in China during 2012-2014,so as to provide basis for setting up related programs at the CDC levels.Methods Based on data gathered through questionnaire surveys run by CDCs from 32 provincial and 5 specifically-designated cities,microsoft excel was used to analyze the current status on management of education and training,for new employees.Results There were 156 management staff members working on education and training programs in 36 CDCs,with 70％ of them having received intermediate or higher levels of education.Large differences were seen on equipment of training hardware in different regions.There were 1 214 teaching staff with 66 percent in the fields or related professional areas on public health,in 2014.5084 new employees conducted pre/post training programs,from 2012 to 2014 with funding as 750 thousand RMB Yuan.99.5％ of the new employees expressed the needs for further training while.74％ of the new staff members expecting a 2-5 day training program to be implemented.79％ of the new staff members claimed that practice as the most appropriate method for training.Conclusions Institutional programs set for education and training at the CDCs need to be clarified,with management team organized.It is important to provide more financial support on both hardware,software and human resources related to training programs which are set for new stuff members at all levels of CDCs.
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<p><b>OBJECTIVE</b>To identify the cause of an outbreak of foot pain syndrome among students from a senior high school in Foshan.</p><p><b>METHODS</b>We defined a suspect case as onset of foot pain/numbness with unknown reason among students and teachers in a school of Foshan city, from February 10 to March 16, 2014. A suspect case was noticed as having both food pain and numbness. All the cases were searched through reviewing medical records in the nearby hospitals and school's clinic, also the records of absenteeism in school. Clinical information was collected from all the students, using a standardized questionnaire. Daily temperature was collected from all the students, between January 1 and March 31, 2014. A 1 : 2 individual matched case-control study was conducted to identify related risk factors on this epidemic. We interviewed all the cases and controls on their diet, physical activities and measures used for warming.</p><p><b>RESULTS</b>A total of 407 case-students were identified, with an attack rate (AR) as 26.5%. The AR was 37.3% in girls, compared to 12.9% in boys. The difference was statistically significant (χ² = 115.1, P < 0.01). Boarding students had a higher AR (31.8%) than the commuting students (16.2%). The difference was statistically significant (χ² = 43.2, P < 0.01). In girls, boarding students had higher AR (46.1%) than those commuting students (18.5%). The difference was statistically significant (χ² = 61.4, P < 0.01). No statistically significant difference was found between boarding or commuting students in boys. Outdoor temperature was coming down from 23 °C on February 6 to 6 °C on February 13, but gradually rose to 23 °C on February 28. There was a positive relationship (r = 0.65, P = 0.002) noticed between daily maximum temperature and the number of cases during February 13-28. Results from this case-control study showed that factors as lacking physical activities (OR = 2.8, 95% CI: 1.5-5.6), feeling cold in bed (OR = 3.0, 95% CI: 1.3-7.0) and having experienced similar symptoms (OR = 3.4, 95% CI: 1.1-11.0) could increase the risk of this disease.</p><p><b>CONCLUSION</b>This outbreak was possibly caused by the abrupt fluctuation of temperature within a short period.</p>
Subject(s)
Female , Humans , Male , Case-Control Studies , China , Epidemiology , Disease Outbreaks , Foot Diseases , Epidemiology , Pain , Epidemiology , Residence Characteristics , Risk Factors , Schools , Students , Surveys and Questionnaires , Syndrome , Temperature , Time Factors , TransportationABSTRACT
<p><b>OBJECTIVE</b>Field surveys were performed under WHO recommended validation procedures, using the Lot Quality Assurance-Cluster Sample(LQA-CS)method to validate the elimination status regarding neonatal tetanus in China.</p><p><b>METHODS</b>LQA-CS surveys were conducted in two areas under the highest risk of neonatal tetanus-Jiangmen prefecture in Guangdong and Hechi in Guangxi. Random sampling method was conducted on 96 survey clusters in each prefecture with 12 eligible live births(live birth born one year before the survey)for each cluster, by trained investigators.</p><p><b>RESULTS</b>There were 1 153 eligible live births from 23 465 families surveyed in Jiangmen and 1 152 eligible live births from 21 623 families being studied in Hechi. All the indices on quality control were strictly followed. There was no neonatal tetanus case which met the criteria of neonatal elimination found in either of the areas. Data showed that neonatal tetanus had been eliminated in both Jiangmen and Hechi cities.</p><p><b>CONCLUSION</b>Since both Jiangmen and Hechi were cities having the highest-risk in China, it was most likely that neonatal tetanus had also been eliminated in other prefectures at lower risk. Elimination programs on MNT was therefore considered validate in China when the study was carried out. However, the achievements needed to be maintained.</p>
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Humans , Infant, Newborn , China , Epidemiology , Lot Quality Assurance Sampling , Tetanus , EpidemiologyABSTRACT
Objectives To summary and compare the different seroconversion rates after the primary vaccination for the Japanese encephalitis (JE),and to evaluate the serological effect of 3 kinds of JE vaccines.Method Searching "CHKD","Wanfang" database and "EMCC" databases,the studies of the immunogenicity after the primary JEV vaccination,all randomized controlled trials or non-randomized controlled trials were included,and statistical analysis were made by RevMan 4.2.10 software.Results A total of 12 literatures were included,7 studies had control groups.The seroconversion rates after the primary vaccination,JEV-L,JEV-I (Vero) and JEV-I(PHK),were 86% (95% CI:80% ～ 91%),83% (95% CI:72% ～ 94%) and 64% (95% CI:58% ～ 69%) respectively.Comparing the seroconversion rates of the 3 kinds of vaccines after primary immunization,the rate of JEV-I (Vero) was significantly higher than the rate of JEVI(PHK),other comparisons were no significant difference.Conclusion The serological effects of JEV-L and JEV-I (Vero) after the primary vaccination were higher than that of JEV-I (PHK).
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<p><b>OBJECTIVE</b>To analyse the genetic relationship of local strains of dengue type 1 viruses isolated in different years and regions from Guangdong Province, and to explore the genetic links with strains of adjacent countries by comparing with the sequences of relevant strains in Genbank.</p><p><b>METHODS</b>The viral RNAs were extracted and used for one-step reverse transcriptase polymerase chain reaction (RT-PCR) to amplify the partial nucleotide fragments in E/NS1 gene junction which were then cloned into the plasmid pBluescript II SK for sequencing, the results were analysed by DNASTAR software.</p><p><b>RESULTS</b>The phylogenetic tree of the sequenced 14 strains of dengue type 1 viruses branches into two genotypic groups. The nucleotide sequences showed a maximal homologies of 99.2% with Indonesia strains, 100% with Philippines strains and 98.8% with Thailand strains.</p><p><b>CONCLUSIONS</b>The dengue type 1 viruses of Guangdong Province are closely related to the Philippines, Indonesia and Thailand strains, which may indicate the possibility of importation from those countries.</p>
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Base Sequence , China , Dengue Virus , Classification , Genetics , Genes, Viral , Genetics , Sequence Analysis, DNA , Sequence Homology, Nucleic AcidABSTRACT
<p><b>OBJECTIVE</b>To determine the cause of acute poisoning occurred in a factory in Yangjiang city, Guangdong province.</p><p><b>METHODS</b>In a cross-sectional study, interviews were conducted with the administrators of the factory and the local physician. A review was conducted on the water system used for industrial purposes and a separate system used by workers for drinking water. Treatment and discharge of industrial waste water were examined. Face-to-face interview was conducted to identify risk of exposure for illness among workers.</p><p><b>RESULTS</b>A total number of 36 cases were identified in the plant and the attack rate was 16.4% (36/220). The incubation period (time between drinking polluted water and the onset of symptoms) had a median of 90 minutes (range: 30 - 230 minutes). Consuming water at the factory increased the attack rate and a dose-response effect was identified (chi(2)(trend) = 79.115, P < 0.01). The nitrite content of residuals in drinking water exceeded the WHO standard (1 ppm).</p><p><b>CONCLUSIONS</b>The accident of acute poisoning was due to drinking water contaminated with sodium nitrite. The prevention of drinking water contaminated by toxic chemicals like sodium nitrite, and the design of industrial and potable water supply system need to be carefully reviewed. Regulations should be developed and enforced to minimize the impact of industrial waste water discharges to guarantee the access to clean drinking water.</p>
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Adolescent , Adult , Female , Humans , Male , Middle Aged , Acute Disease , Industrial Waste , Nitrites , Poisoning , Water Pollutants, Chemical , Poisoning , Water SupplyABSTRACT
<p><b>OBJECTIVE</b>To determine the epidemiological characteristics and risk factors of Dengue fever in Guangdong province in 1990-2000, and to develop the strategy for its prevention and control.</p><p><b>METHODS</b>Sequential of the partial nucleotide fragments in E/NS1 gene junction was analysed.</p><p><b>RESULTS</b>A total of 9,747 cases were reported with three deaths in Guangdong province, 1990-2000. The average incidence was 1.27 per 10,000 (range: 0-9.75 per 10,000). Outbreaks were commonly seen, with 13 cities (61.9%) involved, but most of the cases occurred in Guangzhou, Chaozhou, Zhaoqing and Foshan cities. Numbers of cases reported monthly were gathered with sporadic imported cases reported from January to June while the period of epidemics was from July to December. Sex ratio of patients was 1.04, but all age group was susceptible. Four sero-types of Dengue virus were found during these epidemics. The partial nucleotide fragments in E/NS1 gene junction of 12 isolated viruses were sequenced and 2 sub-gene types were identified in Guangdong province. The clinical symptoms seemed typical. Social and natural factors were responsible for the epidemic of Dengue fever in the regions.</p><p><b>CONCLUSION</b>The epidemic of Dengue fever in Guangdong was closely related to the situations of neighboring countries, indicating the possibility of importation of virus from these countries. The epidemics usually started with imported cases. However, the endemic nature of the disease had not been identified yet.</p>